Окислительный стресс при кератоконусе проявляется в слезной жидкости и стромальных клетках и купируется в клеточной культуре сульфорафаном

Oxidative Stress in Keratoconus Is Evident in Tear Fluid and Stromal Cells and Alleviated in Cell Culture by Sulforaphane.

Keratoconus (KC) is a common eye disease characterized by progressive corneal thinning and weakening resulting in irregular astigmatism, scarring, and vision loss.^1–4 At the corneal tissue level KC is associated with abnormal epithelial thickening, loss of stromal keratocytes and reduced extracellular matrix (ECM) deposition.^5–10 Although many cases can be managed by corneal collagen crosslinking and optical correction, with glasses or contact lenses, severe cases require corneal transplantation.^11–13