Кросслинкинг EpiSmart при кератоконусе: исследование 2-й фазы

EpiSmart Crosslinking for Keratoconus: A Phase 2 Study.

Keratoconus causes an asymmetry of corneal shape and thickness which can markedly impair vision due to progressive corneal thinning, steepening, and resultant irregular astigmatism. Recent population-based epidemiological research using modern topographic or tomographic diagnostics has shown a prevalence of 1% to 4%, with significant regional and ethnic variation,^1–4 suggesting a large unmet need for noninvasive treatment. Current nonsurgical treatments include soft or rigid contact lenses or spectacles. As the disease progresses, these treatments typically do not provide adequate functional improvement. Implantable intracorneal ring segments can improve visual acuity in some cases, but they do not prevent disease progression and can be associated with significant complications. Historically, many patients with keratoconus have required corneal transplantation due to disease progression.